Clinical Workflow
An evidence-based framework for GI health monitoring, combining microbiome intelligence, clinical biomarkers, and visualization to support informed care decisions.
GI Health Monitoring Workflow
GI Assessment
Comprehensive symptom evaluation, family history, and risk factor analysis to determine appropriate testing tier.
Microbiome Test
Strain Level ID Microbiome™ whole-genome sequencing analysis to identify bacterial imbalances and dysbiosis patterns.
Blood & Stool Assays
Blood biomarkers and stool assays (Calprotectin) to assess inflammation, immune response, and digestive function.
VCE (If Indicated)
Video Capsule Endoscopy for direct visualization of small bowel when clinical triggers are met (Platinum tier).
Longitudinal Monitoring
Ongoing tracking and trend analysis with clinician oversight to monitor stability, change, or emerging patterns over time.
Patient Stratification Guide
Prebiotic & Probiotic Protocol Assignment
Based on your Strain Level ID Microbiome™ profile, ProteusDx™ provides personalized nutritional and probiotic guidance to support digestive balance and overall gut wellness.
Your Strain Level ID Microbiome™ results determine which support approach works best for you. We identify your microbiome pattern and match it to one of four personalized support profiles.
Each profile guides specific probiotic strains, prebiotic types, and sequencing strategies designed to support your unique gut ecosystem without causing discomfort.
We don't start everything at once. Based on your profile, we introduce probiotics and prebiotics in a carefully sequenced way to maximize comfort and tolerance.
This phased approach reduces bloating, supports better adherence, and allows your gut ecosystem to adapt gradually for sustainable, long-term gut wellness.
Four Microbiome Support Profiles
Low Diversity Profile
Reduced beneficial bacteria and lower microbial resilience
Approach: Broad-spectrum probiotics first, then gentle prebiotics
Goal: Restore ecosystem diversity and improve digestive resilience
SCFA Deficiency Profile
Low short-chain fatty acid production despite normal diversity
Approach: Prebiotics first to feed existing beneficial microbes
Goal: Support metabolic function and gut lining health
Dysbiosis Pattern Profile
Imbalanced microbial composition with fermentation sensitivity
Approach: Targeted, low-dose probiotics; delay prebiotics initially
Goal: Stabilize gut environment without worsening symptoms
Balanced Maintenance Profile
Healthy diversity and balanced microbial function
Approach: Food-first strategy with optional situational support
Goal: Maintain resilience and optimize long-term gut wellness
How Personalized Support Works
Microbiome Analysis
Your Strain Level ID Microbiome™ results identify your unique microbial composition, diversity patterns, and functional capacity to determine your support profile.
Personalized Protocol
We match your profile to specific probiotic strains and prebiotic types, then sequence their introduction to maximize comfort and minimize digestive discomfort.
Ongoing Optimization
Reassessment at 90-120 days allows us to track progress, adjust recommendations, and optimize your gut wellness journey over time.
Why Phased Introduction?
Introducing probiotics and prebiotics gradually allows your gut ecosystem to adapt comfortably, reducing bloating and digestive discomfort while maximizing long-term tolerance and adherence.
Prevents Overwhelm
Starting all supplements at once can trigger bloating, gas, and discomfort, especially in sensitive or dysbiotic profiles.
Builds Tolerance
Gradual introduction allows your microbiome to adapt to new strains and fibers, improving comfort and reducing dropout rates.
Optimizes Outcomes
Sequenced protocols allow us to identify what works best for you and adjust based on your individual response.
12-Week Phased Protocol Timeline
WEEKS 0-2
Baseline Assessment
Complete Strain Level ID Microbiome™ testing. Receive personalized profile assignment (A, B, C, or D). Begin symptom tracking.
Introduce first intervention based on profile: probiotics (Profile A, C) or prebiotics (Profile B). Low dose, monitor tolerance.
WEEKS 2-4
Phase 1 Introduction
WEEKS 4-8
Phase 2 Expansion
Add second intervention if tolerated. Gradually increase dosage. Continue symptom monitoring and tolerance assessment.
Full protocol implementation. Optimize dosing based on response. Prepare for 90-120 day reassessment and potential retesting.
WEEKS 8-12
Full Protocol & Optimization
Note: Timeline may be adjusted based on individual tolerance and profile-specific needs. Profile C (Dysbiosis) may require slower progression, while Profile D (Balanced) may follow a more flexible schedule.
Wellness Support Statement
ProteusDx™ prebiotic and probiotic recommendations are designed to support digestive wellness and microbiome balance. They are not intended to diagnose, treat, cure, or prevent any disease. Individual tolerance may vary. Recommendations are based on your Strain Level ID Microbiome™ profile as part of a personalized wellness plan.
VCE Decision Logic
Obscure GI Bleeding
Iron-deficiency anemia + Negative FIT + Non-diagnostic scopes
Suspected SB Crohn's
High Calprotectin (>150) + High Genetic Risk + Non-diagnostic scopes
Hereditary Surveillance
Pathogenic mutation in STK11 or SMAD4/BMPR1A
Refractory Celiac
Confirmed Celiac + Failed GF Diet + Ongoing Inflammation