Clinical Partnership Proposal

Integrating ProteusDx™ for Advanced Gastrointestinal Diagnostics

Introduction

ProteusDx™ offers a transformative approach to gastrointestinal healthcare, moving beyond traditional symptom management to a proactive, data-driven model of risk stratification and personalized care. This proposal outlines a partnership opportunity for your practice to integrate the ProteusDx™ clinical workflow, enhancing diagnostic accuracy, optimizing patient outcomes, and positioning your practice at the forefront of GI innovation.

Our platform combines advanced microbiome analysis, biomarker testing, and, when necessary, state-of-the-art imaging to provide a comprehensive view of each patient's unique GI health. By adopting our tiered system, your practice can deliver a tailored level of care that matches the clinical needs of every patient, from wellness-focused individuals to those with complex, symptomatic conditions.

The ProteusDx™ Advantage

Integrating ProteusDx™ into your clinical practice offers significant advantages:

Enhanced Diagnostic Precision

Our multi-modal approach, combining biologic and anatomic assessments, provides a more complete picture than conventional testing alone, enabling more accurate differential diagnoses.

Personalized Patient Care

By stratifying patients into clear tiers, you can offer personalized treatment pathways, from lifestyle and dietary recommendations to advanced diagnostic interventions.

Proactive and Preventive Medicine

The Gold and Platinum tiers are designed to identify subclinical inflammation and other early warning signs, allowing for proactive interventions that can prevent disease progression.

Efficient and Cost-Effective Workflow

Our risk stratification model helps to avoid unnecessary invasive procedures by reserving advanced diagnostics, like Video Capsule Endoscopy, for patients with the highest clinical need.

Tiered Clinical Workflow

ProteusDx™ offers a three-tiered model to accommodate a wide range of patient needs. Each tier provides a progressively deeper level of investigation, ensuring that the intensity of the evaluation matches the clinical suspicion.

Silver Tier

Foundation

OmniGI Core Microbiome WGS (Stool)

Whole-genome sequencing of the gut microbiome.

Primary Use Case:

Wellness and optimization for asymptomatic individuals seeking dietary, lifestyle, and gut health insights.

Gold Tier

Comprehensive

OmniGI Insight

Includes all Silver components plus Blood Biomarkers and a Stool Assay (Calprotectin).

Primary Use Case:

Diagnostic and monitoring tier for symptomatic patients and those with known or suspected inflammatory GI conditions.

Platinum Tier

Advanced

OmniGI 360

Includes all Gold components plus Video Capsule Endoscopy (VCE) for complete small bowel anatomic assessment.

Primary Use Case:

Comprehensive diagnostic and monitoring tier for patients with alarming symptoms or suspected small bowel pathology.

Implementation and Integration

Integrating the ProteusDx™ workflow into your practice is a streamlined process designed for minimal disruption and maximum efficiency:

1

Initial Consultation and Onboarding

Our team will work with your practice to understand your specific needs and tailor an implementation plan. We will provide comprehensive training for your clinical and administrative staff on the ProteusDx™ platform, test ordering, and result interpretation.

2

Patient Assessment and Tier Selection

Your clinicians will continue to perform initial patient assessments as usual. Based on symptoms, risk factors, and clinical history, they will use the ProteusDx™ decision tree to recommend the appropriate tier (Silver, Gold, or Platinum).

3

Sample Collection and Logistics

ProteusDx™ provides all necessary sample collection kits (for stool and blood) for your practice. We have established a seamless logistics network to ensure timely and reliable sample transportation to our certified laboratories.

4

Results and Reporting

Test results are delivered through a secure, user-friendly online portal. Our reports are designed to be clear, concise, and clinically actionable, providing you with the insights needed to guide patient management.

5

Ongoing Support

ProteusDx™ is committed to your success. We offer ongoing clinical support to assist with result interpretation and answer any questions you may have.

Coming Q1 2026

Future Innovations: Guided Wellness Protocol

ProteusDx™ is dedicated to continuous innovation. In Q1 2026, we will be launching our Guided Wellness Protocol, a groundbreaking feature that will be directly integrated with our microbiome test results.

This subscription-based service will leverage microbiome data to activate personalized gut wellness designed to address specific dysfunctions, such as:

  • Low microbial diversity
  • Reduced Short-Chain Fatty Acid (SCFA) production
  • Elevated inflammatory taxa
  • Gut barrier permeability
  • Gut-brain axis imbalances

This upcoming feature will further enhance the personalization of care, offering targeted individualized interventions based on each patient's unique biologic profile.

Ready to Partner With Us?

We are excited about the prospect of partnering with your practice to bring the future of gastrointestinal healthcare to your patients. For more information or to schedule a detailed discussion, please contact us.